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专利概况
专利名称 PHARMACEUTICAL TABLETS CONTAINING ERLOTINIB AS ACTIVE INGREDIENT
申请号 JP2017184473 申请日
公开(公告)号 JP2019059685A 公开(公告)日
申请(专利权)人 NIPPON KAYAKU KK 发明人 AOKI SUSUMU
专利来源 国家知识产权局 转化方式
摘要

To provide a pharmaceutical tablet containing as an active ingredient erlotinib hydrochloride that accelerate the elution of an active ingredient in a neutral medium, such as water and has quick disintegrability.SOLUTION : A pharmaceutical formulation using an active ingredient compounded with A and B crystalline polymorphisms of erlotinib hydrochloride and further using a binder and a disintegrant exerted the elution of 25% or more in 30 minutes, preferably 40% or more in 30 minutes in the dissolution test with water according to the Japanese Pharmacopoeia Dissolution Test Method 2 (paddle method), and a tablet having disintegratability of tablets within 3 minutes in water according to the Japanese Pharmacopoeia disintegration test was obtained.SELECTED DRAWING : None

参与列表

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