The invention relates to a phenol derivative and the preparation method and use in medicine thereof, and in particular, relates to a phenol derivative as shown in the general formula (A), or stereoisomers, solvates, metabolites, prodrugs, pharmaceutical acceptable salts or eutectic crystals thereof, and the preparation method thereof, a pharmaceutical composition comprising the same and use of the compounds or composition of the invention in the field of the central nervous system, wherein the definition of each substituent in general formula (A) is the same as the definition in the description.