专利名称 | MORPHINAN DERIVATIVE AND MEDICAL USAGE THEREOF | ||
申请号 | EP16859938 | 申请日 | |
公开(公告)号 | EP3369736A4 | 公开(公告)日 | |
申请(专利权)人 | University of Tsukuba | 发明人 | NAGASE Hiroshi; YAMAMOTO Naoshi; IRUKAYAMA Yoko; SAITOH Tsuyoshi; YANAGISAWA Masashi; NAGUMO Yasuyuki |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
The purpose of the present invention is to provide a compound useful as a prophylactic or therapeutic agent for various diseases and symptoms related to orexin receptors, and a medical usage of the same. The present invention provides a morphinan derivative represented by the general formula (I) below or a pharmaceutically acceptable acid addition salt thereof, the morphinan derivative having excellent selectivity for and antagonism against orexin receptors and excellent therapeutic and prophylactic effects on drug dependence, and an orexin receptor antagonist and a therapeutic or prophylactic agent for drug dependence each containing it as an active ingredient. |
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