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专利概况
专利名称 IMMUNOMODULATORY AND ANTIVIRAL AGENT BASED ON (2-((COUMARIN-7-YL)OXY)ETHYL) 3-HYDROXY-20(29)-LUPEN-28-OATE
申请号 RU2018138717 申请日
公开(公告)号 RU2686743C1 公开(公告)日
申请(专利权)人 OBSHCHESTVO S OGRANICHENNOJ OTVETSTVENNOSTYU "SIR" 发明人 Abyshev Azad Ziyad ogly; Nguen Kong Bang; Shtro Anna Andreevna; Abyshev Rashad Azad ogly; Ivkin Dmitrij Yurevich; Karavaeva Anna Vladimirovna; Chekerda Elena Viktorovna; Nguen Tkhi Khaj Ien
专利来源 国家知识产权局 转化方式
摘要

FIELD : medicine.SUBSTANCE : invention refers to medicine and chemical-pharmaceutical industry and concerns a new immunomodulatory and antiviral agent based on a hybrid molecule of triterpenoid-coumarin derivatives, namely (2-((coumarin-7-yl)oxy)ethyl) 3-hydroxy 20(29)-lupen-28-oate.EFFECT : declared compound has immunomodulatory properties, having an effect on activation of the humoral response, and expressed antiviral activity against influenza virus A/California/07/09 (H1N1)pdm09 in Balb/c mice in therapeutic and prophylactic mode of application in doses of 10 mg/kg, can be used in medical practice in treating and preventing viral infections.1 cl, 6 dwg, 2 tbl, 3 ex

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