| 专利名称 | IMMUNOMODULATORY AND ANTIVIRAL AGENT BASED ON (2-((COUMARIN-7-YL)OXY)ETHYL) 3-HYDROXY-20(29)-LUPEN-28-OATE | ||
| 申请号 | RU2018138717 | 申请日 | |
| 公开(公告)号 | RU2686743C1 | 公开(公告)日 | |
| 申请(专利权)人 | OBSHCHESTVO S OGRANICHENNOJ OTVETSTVENNOSTYU "SIR" | 发明人 | Abyshev Azad Ziyad ogly; Nguen Kong Bang; Shtro Anna Andreevna; Abyshev Rashad Azad ogly; Ivkin Dmitrij Yurevich; Karavaeva Anna Vladimirovna; Chekerda Elena Viktorovna; Nguen Tkhi Khaj Ien |
| 专利来源 | 国家知识产权局 | 转化方式 | |
| 摘要 |
FIELD : medicine.SUBSTANCE : invention refers to medicine and chemical-pharmaceutical industry and concerns a new immunomodulatory and antiviral agent based on a hybrid molecule of triterpenoid-coumarin derivatives, namely (2-((coumarin-7-yl)oxy)ethyl) 3-hydroxy 20(29)-lupen-28-oate.EFFECT : declared compound has immunomodulatory properties, having an effect on activation of the humoral response, and expressed antiviral activity against influenza virus A/California/07/09 (H1N1)pdm09 in Balb/c mice in therapeutic and prophylactic mode of application in doses of 10 mg/kg, can be used in medical practice in treating and preventing viral infections.1 cl, 6 dwg, 2 tbl, 3 ex |
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