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专利概况
专利名称 ENTECAVIR INTERMEDIATE AND SYNTHESIS METHOD THEREFOR, AND METHOD FOR SYNTHESIZING ENTECAVIR
申请号 WOCN18107397 申请日
公开(公告)号 WO2019080686A1 公开(公告)日
申请(专利权)人 LAUNCH PHARMA TECHNOLOGIES LTD 发明人 JIN Yehua; QIU Fayang; XU Hua; WANG Fang
专利来源 国家知识产权局 转化方式
摘要

Disclosed are an entecavir intermediate, a preparation method for the intermediate and a method for preparing entecavir using the intermediate. The synthesis methods for entecavir and the intermediate thereof in the present invention have the advantages of a controllable chirality, a high yield and a high product purity. Moreover, the raw materials have extensive sources, the reagents are inexpensive and readily available, the reaction is simple, and the operation is simple, environmentally friendly, and suitable for industrialized scaled-up production.

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