PROBLEM TO BE SOLVED : To provide a method for treatment of a neurological or movement disorder, e.g., Parkinson' s disease.SOLUTION : The method for treatment comprises, to a subject in need of treatment, parenteral administration of a composition comprising carbidopa or a pharmaceutically acceptable salt thereof and levodopa or a pharmaceutically acceptable salt thereof, and concomitant oral administration of a catechol-O-methyl transferase (COMT) inhibitor, e.g., entacapone or tolcapone.SELECTED DRAWING : NoneCOPYRIGHT : (C)2019, JPO&INPIT