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专利概况
专利名称 (2S)-N-[(1S)-1-CYANO-2-PHENYLETHYL]-1, 4-OXAZEPANE-2-CARBOXAMIDES AS DIPEPTIDYL PEPTIDASE 1 INHIBITORS
申请号 JP2019005300 申请日
公开(公告)号 JP2019070029A 公开(公告)日
申请(专利权)人 ASTRAZENECA AKTIEBOLAG 发明人 HANS ROLAND LOENN; STEPHEN CONNOLLY; STEVEN SWALLOW; STAFFAN PO KARLSSON; CARL JOHAN AURELL; JOHN FRITIOF PONTEN; KEVIN JAMES DOYLE; AMANDA VAN DE POL; GRAHAM PETER JONES; DAVID WYN WATSON; JAQUELINE ANNE MACRITCHIE; NICHOLAS JOHN PALMER
专利来源 国家知识产权局 转化方式
摘要

PROBLEM TO BE SOLVED : To provide compounds useful for treating and/or preventing clinical conditions including respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD). SOLUTION : The present invention provides (2S)-N-[(1S)-1-cyano-2-phenylethyl]-1, 4-oxazepane-2-carboxamide compounds, represented by a following formula. [R1 is a phenyl group, and is unsubstituted, or substituted with F, Cl, an azetidine ring, a pyrrolidine ring, a piperidine ring-containing heterocycle or the like]. SELECTED DRAWING : None COPYRIGHT : (C)2019, JPO&INPIT

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