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专利概况
专利名称 NOVEL TRICYCLIC COMPOUNDS AS ANTICANCER AGENTS
申请号 JP2019002078 申请日
公开(公告)号 JP2019070014A 公开(公告)日
申请(专利权)人 BRISTOL MYERS SQUIBB COMPANY 发明人 DEREK J NORRIS; GEORGE V DELUCCA; ASHVINIKUMAR V GAVAI; CLAUDE A QUESNELLE; PATRICE GILL; DANIEL O' MALLEY; WAYNE VACCARO; FRANCIS Y LEE; MIKKEL V DEBENEDETTO; ANDREW P DEGNAN; FANG HAIQUAN; MATTHEW D HILL; HUANG HONG; WILLIAM D SCHMITZ; JOHN E STARRETT JR; HAN WEN CHING; JOHN S TOKARSKI; SUNIL KUMAR MANDAL
专利来源 国家知识产权局 转化方式
摘要

PROBLEM TO BE SOLVED : To provide novel tricyclic compounds, pharmaceutical compositions comprising the compounds, and methods of using them, for example, for the treatment or prophylaxis of certain cancers, and their use in therapy. SOLUTION : The present invention provides tricyclic compounds of a formula (I), and pharmaceutically acceptable compounds having the compounds. In the formula, A is optionally substituted heterocyclo or optionally substituted heteroaryl; X and Y represent H, optionally substituted alkyl or the like; Z is H, halogen or the like; R1 independently represents one or more H, halogen or the like; R2 represents H, halogen or the like; R7 is H, optionally substituted alkyl or the like. SELECTED DRAWING : None COPYRIGHT : (C)2019, JPO&INPIT

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