专利名称 | NOVEL TRICYCLIC COMPOUNDS AS ANTICANCER AGENTS | ||
申请号 | JP2019002078 | 申请日 | |
公开(公告)号 | JP2019070014A | 公开(公告)日 | |
申请(专利权)人 | BRISTOL MYERS SQUIBB COMPANY | 发明人 | DEREK J NORRIS; GEORGE V DELUCCA; ASHVINIKUMAR V GAVAI; CLAUDE A QUESNELLE; PATRICE GILL; DANIEL O' MALLEY; WAYNE VACCARO; FRANCIS Y LEE; MIKKEL V DEBENEDETTO; ANDREW P DEGNAN; FANG HAIQUAN; MATTHEW D HILL; HUANG HONG; WILLIAM D SCHMITZ; JOHN E STARRETT JR; HAN WEN CHING; JOHN S TOKARSKI; SUNIL KUMAR MANDAL |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
PROBLEM TO BE SOLVED : To provide novel tricyclic compounds, pharmaceutical compositions comprising the compounds, and methods of using them, for example, for the treatment or prophylaxis of certain cancers, and their use in therapy. SOLUTION : The present invention provides tricyclic compounds of a formula (I), and pharmaceutically acceptable compounds having the compounds. In the formula, A is optionally substituted heterocyclo or optionally substituted heteroaryl; X and Y represent H, optionally substituted alkyl or the like; Z is H, halogen or the like; R1 independently represents one or more H, halogen or the like; R2 represents H, halogen or the like; R7 is H, optionally substituted alkyl or the like. SELECTED DRAWING : None COPYRIGHT : (C)2019, JPO&INPIT |
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