专利名称 | NEP INHIBITORS FOR TREATING DISEASES CHARACTERIZED BY ATRIAL EXPANSION OR REMODELING | ||
申请号 | JP2018228452 | 申请日 | |
公开(公告)号 | JP2019069954A | 公开(公告)日 | |
申请(专利权)人 | NOVARTIS AG | 发明人 | CHRISTOPH SCHUMACHER; THOMAS HOLBRO |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
PROBLEM TO BE SOLVED : To provide NEP inhibitor prodrugs or NEP inhibitors or pharmaceutically acceptable salt thereof for treating, preventing or delaying progression of diseases characterized by atrial expansion or remodeling.SOLUTION : Disclosed herein is a NEP inhibitor prodrug N-(3-carboxy-1-oxopropyl)-(4S)-p-phenylphenylmethyl)-4-amino-(2R)-methylbutanoic acid ethylester or pharmaceutically acceptable salt thereof. Also disclosed is a NEP inhibitor N-(3-carboxy-1-oxopropyl)-(4S)-p-phenylphenylmethyl)-4-amino-(2R)-methylbutanoic acid or pharmaceutically acceptable salt thereof.SELECTED DRAWING : NoneCOPYRIGHT : (C)2019, JPO&INPIT |
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