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专利概况
专利名称 NEP INHIBITORS FOR TREATING DISEASES CHARACTERIZED BY ATRIAL EXPANSION OR REMODELING
申请号 JP2018228452 申请日
公开(公告)号 JP2019069954A 公开(公告)日
申请(专利权)人 NOVARTIS AG 发明人 CHRISTOPH SCHUMACHER; THOMAS HOLBRO
专利来源 国家知识产权局 转化方式
摘要

PROBLEM TO BE SOLVED : To provide NEP inhibitor prodrugs or NEP inhibitors or pharmaceutically acceptable salt thereof for treating, preventing or delaying progression of diseases characterized by atrial expansion or remodeling.SOLUTION : Disclosed herein is a NEP inhibitor prodrug N-(3-carboxy-1-oxopropyl)-(4S)-p-phenylphenylmethyl)-4-amino-(2R)-methylbutanoic acid ethylester or pharmaceutically acceptable salt thereof. Also disclosed is a NEP inhibitor N-(3-carboxy-1-oxopropyl)-(4S)-p-phenylphenylmethyl)-4-amino-(2R)-methylbutanoic acid or pharmaceutically acceptable salt thereof.SELECTED DRAWING : NoneCOPYRIGHT : (C)2019, JPO&INPIT

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