The present disclosure is related to an ophthalmological solution for neonatal conjunctivitis. With an active ingredient such as azithromycin in ophthalmic single doses for the prophylaxis (prevention) of neonatal conjunctivitis. Susceptible of being applied to all newborn children, with the following advantages : Is totally specific for the most frequent bacteria of the ophthalmia neonatorum, avoiding alterations as severe as blindness, having specificity with the most frequent bacteria, individual and disposable use to avoid direct contamination in the newborn wards due to the misuse of current drugs. Therefore, the present invention is within the technical field of medicine, the use of the present invention in the field of neonatology that at the same time is part of the Pediatrics specialty, and will prevent an infection in the eyes of newborns, since this pathology is known to cause blindness.