FIELD : medicine; pharmaceuticals.SUBSTANCE : invention relates to medicine, specifically to a packaged pharmaceutical product comprising a stable solid pharmaceutical composition and a moisture-impermeable package, wherein said composition contains a homogeneous mixture of a base of amlodipine or amlodipine besylate and bisoprolol fumarate and pharmaceutically acceptable excipients, is packaged in said moisture-impermeable package and further contains less than 0.5?% of weight of active ingredients of compound of formula and where said moisture-proof package is a blister pack of cold molding from composite foil OPA/AL/PVC (foil of oriented polyamide/aluminum/polyvinyl chloride), coated with aluminum membrane foil.EFFECT : invention provides a packaged pharmaceutical product wherein the amount of impurities does not exceed ??% during preparation or during storage until expiry of the composition for at least two years.8 cl, 2 ex, 2 tbl