| 专利名称 | In checkpoint inhibitors used in the prediction of adverse immune related immunological | ||
| 申请号 | JP2018525312 | 申请日 | |
| 公开(公告)号 | JPWO2018003995A1 | 公开(公告)日 | |
| 申请(专利权)人 | 国立大学法人東北大学 | 发明人 | 藤村 卓 |
| 专利来源 | 国家知识产权局 | 转化方式 | |
| 摘要 |
The present invention provides a novel method of obtaining data for predicting the onset of an adverse event due to administration of at least one antibody drug selected from an anti-PD-1 antibody, an anti-PD-L1 antibody, an anti-CTLA4 antibody, and an antigen-binding fragment thereof, or a novel method of predicting the onset of the adverse event. More specifically, the present invention provides a method of obtaining data for predicting the onset of an adverse event or a method of predicting the onset of the adverse event, comprising measuring a level of at least one marker selected from sCD163 and CXCL5 in a biological sample collected from a subject administered the antibody drug. |
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