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专利概况
专利名称 In checkpoint inhibitors used in the prediction of adverse immune related immunological
申请号 JP2018525312 申请日
公开(公告)号 JPWO2018003995A1 公开(公告)日
申请(专利权)人 国立大学法人東北大学 发明人 藤村 卓
专利来源 国家知识产权局 转化方式
摘要

The present invention provides a novel method of obtaining data for predicting the onset of an adverse event due to administration of at least one antibody drug selected from an anti-PD-1 antibody, an anti-PD-L1 antibody, an anti-CTLA4 antibody, and an antigen-binding fragment thereof, or a novel method of predicting the onset of the adverse event. More specifically, the present invention provides a method of obtaining data for predicting the onset of an adverse event or a method of predicting the onset of the adverse event, comprising measuring a level of at least one marker selected from sCD163 and CXCL5 in a biological sample collected from a subject administered the antibody drug.

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