专利名称 | TERIPARATIDE-CONTAINING LIQUID PHARMACEUTICAL COMPOSITION HAVING EXCELLENT STABILITY | ||
申请号 | JP2019008790 | 申请日 | |
公开(公告)号 | JP2019073543A | 公开(公告)日 | |
申请(专利权)人 | ASAHI KASEI PHARMA KK | 发明人 | MIYABE KOHEI; YAMAGUCHI TAKAHIRO; MATSUNAWA YASUHIRO; WATANABE NARUMI |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
PROBLEM TO BE SOLVED : To inhibit the generation of an oxidant in a liquid pharmaceutical syringe preparation containing teriparatide. SOLUTION : This invention relates to a method of inhibiting the generation of an oxidant in a liquid pharmaceutical syringe preparation containing component 1 during its storage, by shielding the preparation from light. The oxidant is a teriparatide oxidant or an acetate thereof in which a 18-th methionine residue from an N terminal of teriparatide is sulfoxidized. The component 1 : a teriparatide oxidant or an acetate thereof. SELECTED DRAWING : None COPYRIGHT : (C)2019, JPO&INPIT |
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