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专利概况
专利名称 TERIPARATIDE-CONTAINING LIQUID PHARMACEUTICAL COMPOSITION HAVING EXCELLENT STABILITY
申请号 JP2019008790 申请日
公开(公告)号 JP2019073543A 公开(公告)日
申请(专利权)人 ASAHI KASEI PHARMA KK 发明人 MIYABE KOHEI; YAMAGUCHI TAKAHIRO; MATSUNAWA YASUHIRO; WATANABE NARUMI
专利来源 国家知识产权局 转化方式
摘要

PROBLEM TO BE SOLVED : To inhibit the generation of an oxidant in a liquid pharmaceutical syringe preparation containing teriparatide. SOLUTION : This invention relates to a method of inhibiting the generation of an oxidant in a liquid pharmaceutical syringe preparation containing component 1 during its storage, by shielding the preparation from light. The oxidant is a teriparatide oxidant or an acetate thereof in which a 18-th methionine residue from an N terminal of teriparatide is sulfoxidized. The component 1 : a teriparatide oxidant or an acetate thereof. SELECTED DRAWING : None COPYRIGHT : (C)2019, JPO&INPIT

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