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专利概况
专利名称 TABLET FORMULATION COMPRISING PEPTIDE AND DELIVERY AGENT
申请号 JP2019007588 申请日
公开(公告)号 JP2019073541A 公开(公告)日
申请(专利权)人 NOVO NORDISK AS 发明人 SIMON BJERREGAARD; SAUERBERG PER; FLEMMING SEIER NIELSEN; BETTY LOMSTEIN PEDERSEN; ERIK SKIBSTED
专利来源 国家知识产权局 转化方式
摘要

PROBLEM TO BE SOLVED : To provide solid compositions comprising a GLP-1 peptide and a delivery agent, such as SNAC, and uses thereof.SOLUTION : The present inventors surprisingly found that requirements for physical parameters of tablets, such as density, porosity and/or crushing strength, and methods of preparation of the tablets according to the present invention provide tablets with improved bioavailability of peptides, such as acylated peptides.SELECTED DRAWING : NoneCOPYRIGHT : (C)2019, JPO&INPIT

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