专利名称 | TABLET FORMULATION COMPRISING PEPTIDE AND DELIVERY AGENT | ||
申请号 | JP2019007588 | 申请日 | |
公开(公告)号 | JP2019073541A | 公开(公告)日 | |
申请(专利权)人 | NOVO NORDISK AS | 发明人 | SIMON BJERREGAARD; SAUERBERG PER; FLEMMING SEIER NIELSEN; BETTY LOMSTEIN PEDERSEN; ERIK SKIBSTED |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
PROBLEM TO BE SOLVED : To provide solid compositions comprising a GLP-1 peptide and a delivery agent, such as SNAC, and uses thereof.SOLUTION : The present inventors surprisingly found that requirements for physical parameters of tablets, such as density, porosity and/or crushing strength, and methods of preparation of the tablets according to the present invention provide tablets with improved bioavailability of peptides, such as acylated peptides.SELECTED DRAWING : NoneCOPYRIGHT : (C)2019, JPO&INPIT |
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