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专利概况
专利名称 PHTHALAZINONES AND ISOQUINOLINONES AS ROCK INHIBITORS
申请号 JP2018242012 申请日
公开(公告)号 JP2019073521A 公开(公告)日
申请(专利权)人 BRISTOL MYERS SQUIBB COMPANY 发明人 PETER W GLUNZ; ZOU YAN; MIMI L QUAN; VLADIMIR LADZIATA
专利来源 国家知识产权局 转化方式
摘要

PROBLEM TO BE SOLVED : To provide novel compounds for treating a cardiovascular disease, a smooth muscle related disease, a fibrotic disease, and the like. SOLUTION : The present invention provides compounds of formula (I), or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, where M is N; L is -CR4R4C(O)-, -OC(O)-, -NR6-; R1 is NR5R5, a carbocycle or a heterocycle ; R2 to R5 are each alkyl, a carbocycle, a heterocycle, or the like; and R6 is H, C1-4 alkyl, or the like. SELECTED DRAWING : None COPYRIGHT : (C)2019, JPO&INPIT

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