专利名称 | PHARMACEUTICAL TABLETS CONTAINING APREPITANT AS ACTIVE INGREDIENT | ||
申请号 | JP2017202269 | 申请日 | |
公开(公告)号 | JP2019073488A | 公开(公告)日 | |
申请(专利权)人 | NIPPON KAYAKU CO LTD | 发明人 | NAKAMURA TAKANORI |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
PROBLEM TO BE SOLVED : To provide pharmaceutical tablets containing aprepitant as active ingredient which exert rapid elution equivalent to capsule formulations.SOLUTION : A pharmaceutical tablet containing aprepitant as an active ingredient and having excellent elution can be provided by using as an excipient a pharmaceutical tablet containing mannitol. Preferably, the mannitol is applied as excipient granules previously granulated together with a disintegrant and the like. Preferably, the aprepitant is applied in a solid dispersion with a water soluble polymer carrier.SELECTED DRAWING : NoneCOPYRIGHT : (C)2019, JPO&INPIT |
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