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专利概况
专利名称 SOLID PREPARATION CONTAINING 4-AMINOBUTANOIC ACID ANALOG AND PRODUCTION METHOD THEREOF
申请号 JP2017200996 申请日
公开(公告)号 JP2019073478A 公开(公告)日
申请(专利权)人 NIPPON CHEMIPHAR CO LTD 发明人 TATSUNO TAKAMITSU; ASHIHARA YUTA; TANIGAWA YUKI; SANO TSUBASA
专利来源 国家知识产权局 转化方式
摘要

PROBLEM TO BE SOLVED : To provide solid preparations in which drug stability is maintained and generation of the spot on a tablet surface is suppressed, in solid preparations containing 4-aminobutanoic acid analog represented by gabapentin and pregabalin.SOLUTION : Provided is a solid preparation produced by a step of wet-granulation from an emulsified liquid containing γ-aminobutanoic acid analog represented by formula (I), a hardened oil, and glycerine fatty acid ester, and a step of drying, as well as by mixing and tableting with an additive a granule in the state of being coated with a hardened oil and glycerine fatty acid ester.SELECTED DRAWING : NoneCOPYRIGHT : (C)2019, JPO&INPIT

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