专利名称 | PHARMACEUTICAL PREPARATION CONTAINING FOSAPREPITANT | ||
申请号 | JP2017199006 | 申请日 | |
公开(公告)号 | JP2019073457A | 公开(公告)日 | |
申请(专利权)人 | NIPPON KAYAKU CO LTD | 发明人 | HIDAKA NOBORU |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
PROBLEM TO BE SOLVED : To provide a pharmaceutical preparation that contains fosaprepitant, which is a phosphorylated prodrug of aprepitant, or a pharmaceutically acceptable salt thereof as an active ingredient, the pharmaceutical preparation having inhibited production of analogs, as the fosaprepitant is known to be susceptible to hydrolysis and unstable.SOLUTION : It is found out that a pharmaceutical preparation containing fosaprepitant or a pharmaceutically acceptable salt thereof and maltose or trehalose can provide a pharmaceutical preparation having inhibited production of analogs.SELECTED DRAWING : NoneCOPYRIGHT : (C)2019, JPO&INPIT |
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