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专利概况
专利名称 FGFR4 inhibitor, preparation method therefor and pharmaceutical use thereof
申请号 AU2017378943 申请日
公开(公告)号 AU2017378943A1 公开(公告)日
申请(专利权)人 Abbisko Therapeutics Co Ltd 发明人 Yang Fei; Deng Haibing; Ying Haiyan; Yu Hongping; Chen Zhui; Xu Yaochang
专利来源 国家知识产权局 转化方式
摘要

Provided are an FGFR4 inhibitor having the structure of formula (I), and a preparation method therefor and the use thereof. The compound has a very strong inhibitory effect on FGFR4 kinase activity and has a very high selectivity, and can be widely used in the preparation of a drug for treating cancers, especially prostate cancer, liver cancer, pancreatic cancer, esophageal carcinomas, gastric cancer, lung cancer, breast cancer, ovarian carcinomas, colon cancer, skin cancer, glioblastomas or rhabdomyosarcomas, and is expected to be developed into a new generation of FGFR4 inhibitor drugs.

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