FIELD : medicine.SUBSTANCE : invention relates to medicine, veterinary science and pharmacology, and concerns treating aseptic and freshly infected soft tissue wounds, specifically relates to methods of stimulating regeneration (ability to accelerate and / or induce regeneration processes) of skin and underlying soft tissues, as well as to medicinal agents possessing regenerative potential, and can be used in dermatology, cosmetology and surgery for treating abrasive, full-layer and scalp wounds. Purpose of the invention is to accelerate the process of wound healing with maximum recovery of damaged tissue structures by applying on the wound surface a preparation containing the protein internalin B 321.EFFECT : method reduces the epithelialization of wounds by activating intracellular signaling pathways leading to accelerated proliferation and cell migration of cells involved in the wound healing process.2 cl, 5 dwg, 5 ex