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专利概况
专利名称 OLIGONUCLEOTIDE SEQUENCE OLIGONUCLEOTIDE SEQUENCE FOR THE NRAS GENE Q61R MUTATION IN THE TUMOR FORMATIONS OF THE THYROID GLAND
申请号 RU2018144732 申请日
公开(公告)号 RU2688189C1 公开(公告)日
申请(专利权)人 Obshchestvo s ogranichennoj otvetstvennostyu "Pervyj onkologicheskij nauchno konsultatsionnyj tsentr" 发明人 Kochergina Nikitskaya Irina Nikolaevna; Vladimirova Ulyana Sergeevna; Rumyantsev Pavel Olegovich
专利来源 国家知识产权局 转化方式
摘要

FIELD : medicine.SUBSTANCE : proposed group of inventions relates to medicine. Disclosed are a method and a kit for detecting Q61R mutation in a NRAS protein in a human tumor tissue sample. Method involves obtaining a sample of biological material taken from a patient, recovering DNA from said sample and carrying out PCR using a kit for detecting Q61R mutation in a NRAS protein.EFFECT : presented group of inventions enables higher specificity and sensitivity of determining the presence of a mutant allele at the Q61R point of the NRAS gene, as well as reducing the probability of process errors during laboratory manipulations.3 cl, 1 dwg, 1 tbl, 1 ex

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