专利名称 | THIAZOLE INNER SALT COMPOUNDS AND PREPARATION METHOD AND USE THEREOF | ||
申请号 | EP14822521 | 申请日 | |
公开(公告)号 | EP3020711B1 | 公开(公告)日 | |
申请(专利权)人 | Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P L A China | 发明人 | LI Song; ZHONG Wu; CAO Shuang; WANG Lili; ZHENG Zhibing; XIAO Junhai; ZHOU Xinbo |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
The present invention pertains to field of pharmaceutical chemicals, and relates to thiazole inner salt compounds, preparation methods and uses thereof. Specifically, the present invention relates to a compound of Formula I, hydrates or pharmaceutically acceptable salts thereof. The compound of Formula I of the present invention is a potent cross-linking protein cleavage agent, has a stable structure, good physical and chemical properties, and good pharmacological activities, and is suitable for large scale production to obtain samples with stable, controllable and reliable quality, thereby being suitable for pharmaceutical development. |
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