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专利概况
专利名称 THIAZOLE INNER SALT COMPOUNDS AND PREPARATION METHOD AND USE THEREOF
申请号 EP14822521 申请日
公开(公告)号 EP3020711B1 公开(公告)日
申请(专利权)人 Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P L A China 发明人 LI Song; ZHONG Wu; CAO Shuang; WANG Lili; ZHENG Zhibing; XIAO Junhai; ZHOU Xinbo
专利来源 国家知识产权局 转化方式
摘要

The present invention pertains to field of pharmaceutical chemicals, and relates to thiazole inner salt compounds, preparation methods and uses thereof. Specifically, the present invention relates to a compound of Formula I, hydrates or pharmaceutically acceptable salts thereof. The compound of Formula I of the present invention is a potent cross-linking protein cleavage agent, has a stable structure, good physical and chemical properties, and good pharmacological activities, and is suitable for large scale production to obtain samples with stable, controllable and reliable quality, thereby being suitable for pharmaceutical development.

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