专利名称 | PHARMACEUTICAL TABLET COMPOSITION COMPRISING BILASTINE FORM 3 AND A WATER-SOLUBLE FILLER | ||
申请号 | WOEP18085448 | 申请日 | |
公开(公告)号 | WO2019097091A1 | 公开(公告)日 | |
申请(专利权)人 | ALFRED E TIEFENBACHER (GMBH CO KG) | 发明人 | GUJJAR Chaitanya Yogananda; UPPALA Susheel Prakash; DONGA Nani Prasad; BANDLA Srimannarayana; RALLABANDI Bala Ramesha Chary; STAVER Ruslan; SCHLEHAHN Hendrik |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
The invention relates to a pharmaceutical composition in the form of a tablet, comprising a) a crystalline form of bilastine according to crystalline (polymorph) form 3, wherein the crystalline form has characteristic peaks at 6.47, 12.81, 15.70, and 17.71 ?0.2 degrees 2-theta in a powder X-ray diffraction pattern, b) a water-soluble filler, and optionally c) a water-insoluble filler. The invention further relates to a method of preparing a pharmaceutical composition in the form of a tablet comprising dry granulation of a blend of the tablet components and compression of the granules to a tablet, or direct compression of a blend to a tablet. The invention relates further to the medical use of the pharmaceutical composition in the treatment of allergic rhino-conjunctivitis and/or urticaria. |
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