PROBLEM TO BE SOLVED : To provide inhibitors which are therapeutically useful as novel kinase inhibitors, particularly IRAK4 inhibitors. SOLUTION : The present invention provides compounds of formula (I), where A, Y, Z, X1, X2, X3, R1, R3 are specific groups. The compounds are useful in treatment and prevention of diseases or disorders, in particular their use in diseases or disorders mediated by a kinase enzyme, particularly IRAK4 enzyme. SELECTED DRAWING : None COPYRIGHT : (C)2019, JPO&INPIT