您好,欢迎来到海南中小企业大数据中心及公共服务平台!     请登录   免费注册
专利概况
专利名称 Substituted hydroxamic acid compounds
申请号 JP2018224004 申请日
公开(公告)号 JP2019077688A 公开(公告)日
申请(专利权)人 UNIV DUKE; UNIV OF NORTH CAROLINA 发明人 ZHOU PEI; ERIC J TOONE; ROBERT A NICHOLAS
专利来源 国家知识产权局 转化方式
摘要

PROBLEM TO BE SOLVED : To provide substituted hydroxamic acid compounds, and in particular, UDP-3-O-(R-3-hydroxydecanoyl)-N-acetylglucosamine deacetylase (LpxC), and methods of using such compounds to treat Gram-negative bacteria infections.SOLUTION : There are disclosed compounds of formulas (I) and (II), and pharmaceutically acceptable salts thereof, where the variables, R, R1, R2, R3, R21, R22, R23, R34, R37, R33, R39, D, Q, Y, X, X1, X3 and X4 are defined herein. These compounds are useful for treating Gram-negative bacteria infections.SELECTED DRAWING : NoneCOPYRIGHT : (C)2019, JPO&INPIT

参与列表

主管部门:海南中小企业服务 | 建设单位:海南商业联合会

版权所有:海南商业联合会 | 备案号:粤ICP备13083911号(ICP加挂服务)@2017