The present invention relates to antigen-recognition constructs against COL6A3 - antigens. The invention provides new constructed especially on T cell receptors (a TCR) based molecules, which are selectively and specific for tumors, the expressing the antigen COL6A3, available. According to the invention are antigen-binding fragments derived therefrom and a TCR COL6A3 in diagnosis, treatment and prevention of cancers expressing COL6A3 useful. Further nucleic acids, according to the invention encoding the antigen-recognition constructs, vectors, comprising said nucleic acids, recombinant cells, which express the antigen-recognizing constructs, and pharmaceutical compositions, the compounds according to the invention comprise be, made available.