FIELD : biotechnology; medicine.SUBSTANCE : invention relates to biotechnology, specifically to calcitonin mimetics, and can be used in medicine. A calcitonin mimetic is a polypeptide with SEQ ID NO : 44, acetylated on the N-terminus and amidated at the C-terminal.EFFECT : invention can be used as a part of pharmaceutical compositions for effective treatment of diabetes mellitus, excess body weight, non-alcoholic fatty dystrophy, osteoporosis or osteoarthritis.20 cl, 17 dwg, 5 tbl, 7 ex