PROBLEM TO BE SOLVED : To provide a lyophilized pharmaceutical composition that suppresses a delay in repreparation time and shows excellent repreparation, and contains bortezomib or a derivative thereof, and a method for producing the same.SOLUTION : The present invention provides a lyophilized pharmaceutical composition that contains bortezomib or a derivative thereof, where the lyophilized pharmaceutical composition has a moisture content of 1.0% or less, preferably 0.5% or less. The content of bortezomib or a derivative thereof is 1-5 mg for each preparation, preferably 2 or 3 mg.SELECTED DRAWING : NoneCOPYRIGHT : (C)2019, JPO&INPIT