专利名称 | SALT OF PHENYLPROPIONAMIDE DERIVATIVE AND PREPARATION METHOD THEREFOR | ||
申请号 | WOCN18119309 | 申请日 | |
公开(公告)号 | WO2019109934A1 | 公开(公告)日 | |
申请(专利权)人 | JIANGSU HENGRUI MEDICINE CO LTD; SHANGHAI HENGRUI PHARMACEUTICAL CO LTD | 发明人 | WANG Lin; YE Jingquan; SHAO Qiyun; FENG Jun; HE Feng; CAO Xiaoli; MA Yahui |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
The present invention provides a salt of a phenylpropionamide derivative and a preparation method therefor. The present invention specifically provides an acetate, hydrochloride, phosphate, citrate, benzoate, or fumarate of 4-amino-1-((2R, 5R, 8R, 14R)-2-(4-aminobutyl)-8-benzyl-5-isobutyl-4, 7, 10-trioxo-14-phenyl-3, 6, 9, 12-tetraazapentadecan-1-acyl)piperidine-4-carboxylic acid, and a preparation method therefor. The salt of the compound of formula (I) of the present invention has good stability, and the simple process thereof facilitates easy operation. The invention is better suited for clinical treatment. |
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