| 专利名称 | PARP/PI3K DOUBLE-TARGET INHIBITOR CONTAINING PYRIDOPYRIMIDINE STRUCTURE | ||
| 申请号 | WOCN18097980 | 申请日 | |
| 公开（公告）号 | WO2019109647A1 | 公开（公告）日 | |
| 申请（专利权）人 | CHINA PHARMACEUTICAL UNIVERSITY; HEFEI INDUSTRIAL PHARMACEUTICAL INSTITUTE CO LTD | 发明人 | XU Yungen; ZHU Qihua; WANG Junwei; LI Hui; CHU Zhaoxing; HE Guangwei |
| 专利来源 | 国家知识产权局 | 转化方式 | |
| 摘要 |
The present invention relates to the field of pharmaceutical chemistry. In particular, the present invention relates to a PARP/PI3K double-target inhibitor (I) containing structures of 5, 6, 7, 8-tetrahydropyrido[3, 4-d]pyrimidine and phthalazin-1(2H)-one and a preparation method thereof. The compound has PARP/PI3K double-target inhibitory activity as proved by pharmacodynamic tests and can be used against a tumor. |
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