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专利概况
专利名称 PHARMACEUTICAL SOLUTIONS, PROCESS OF PREPARATION, AND THERAPEUTIC USES
申请号 JP2019029289 申请日
公开(公告)号 JP2019089837A 公开(公告)日
申请(专利权)人 UCB BIOPHARMA SPRL 发明人 ERIC SCHENKEL; CLAIRE POULAIN; BERTRAND DODELET; FANARA DOMENICO
专利来源 国家知识产权局 转化方式
摘要

PROBLEM TO BE SOLVED : To provide a stable liquid formulation of a 2-oxo-1-pyrrolidine derivative, a process of preparation thereof, and therapeutic uses thereof.SOLUTION : The invention provides an aqueous solution of a pharmaceutical compound being (2S)-2-[(4R)-2-oxo-4-propyl-pyrrolidin-1-yl]butanamide represented by the formula in the figure, which has a pH value between 4.5 and 6.5. The solution may be an injectable solution in which the amount of the pharmaceutical compound is in the range of 0.01 to 200 mg per ml. The solution may be an oral solution in which the amount of the pharmaceutical compound is in the range of 0.01 to 100 mg per ml.SELECTED DRAWING : NoneCOPYRIGHT : (C)2019, JPO&INPIT

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