专利名称 | PHARMACEUTICAL SOLUTIONS, PROCESS OF PREPARATION, AND THERAPEUTIC USES | ||
申请号 | JP2019029289 | 申请日 | |
公开(公告)号 | JP2019089837A | 公开(公告)日 | |
申请(专利权)人 | UCB BIOPHARMA SPRL | 发明人 | ERIC SCHENKEL; CLAIRE POULAIN; BERTRAND DODELET; FANARA DOMENICO |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
PROBLEM TO BE SOLVED : To provide a stable liquid formulation of a 2-oxo-1-pyrrolidine derivative, a process of preparation thereof, and therapeutic uses thereof.SOLUTION : The invention provides an aqueous solution of a pharmaceutical compound being (2S)-2-[(4R)-2-oxo-4-propyl-pyrrolidin-1-yl]butanamide represented by the formula in the figure, which has a pH value between 4.5 and 6.5. The solution may be an injectable solution in which the amount of the pharmaceutical compound is in the range of 0.01 to 200 mg per ml. The solution may be an oral solution in which the amount of the pharmaceutical compound is in the range of 0.01 to 100 mg per ml.SELECTED DRAWING : NoneCOPYRIGHT : (C)2019, JPO&INPIT |
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