专利名称 | LYOPHILIZED PHARMACEUTICAL COMPOSITION | ||
申请号 | JP2017218901 | 申请日 | |
公开(公告)号 | JP2019089725A | 公开(公告)日 | |
申请(专利权)人 | NIPRO CORP | 发明人 | MATSUBARA NORIFUMI; SHIROUCHI YUTAKA; INOUE HIROYUKI |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
PROBLEM TO BE SOLVED : To provide micafungin-containing lyophilized pharmaceutical compositions capable of suppressing an increase in the amount of analogue during storage by a stabilizer different from conventional arts.SOLUTION : The lyophilized pharmaceutical composition of the present invention comprises micafungin or a pharmaceutically acceptable salt of micafungin, or micafungin or a hydrate of a pharmaceutically acceptable salt of micafungin, and a first stabilizer, the first stabilizer being at least one selected from the group consisting of gluconic acid, inorganic salts of gluconic acid, and inositol. In addition, a preparation for injection contains a lyophilized pharmaceutical composition and at least one solvent selected from the group consisting of physiological saline solution, glucose injection solution, and replacement fluid, the lyophilized pharmaceutical composition being dissolved in a solvent.SELECTED DRAWING : NoneCOPYRIGHT : (C)2019, JPO&INPIT |
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