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专利概况
专利名称 LYOPHILIZED PHARMACEUTICAL COMPOSITION
申请号 JP2017218901 申请日
公开(公告)号 JP2019089725A 公开(公告)日
申请(专利权)人 NIPRO CORP 发明人 MATSUBARA NORIFUMI; SHIROUCHI YUTAKA; INOUE HIROYUKI
专利来源 国家知识产权局 转化方式
摘要

PROBLEM TO BE SOLVED : To provide micafungin-containing lyophilized pharmaceutical compositions capable of suppressing an increase in the amount of analogue during storage by a stabilizer different from conventional arts.SOLUTION : The lyophilized pharmaceutical composition of the present invention comprises micafungin or a pharmaceutically acceptable salt of micafungin, or micafungin or a hydrate of a pharmaceutically acceptable salt of micafungin, and a first stabilizer, the first stabilizer being at least one selected from the group consisting of gluconic acid, inorganic salts of gluconic acid, and inositol. In addition, a preparation for injection contains a lyophilized pharmaceutical composition and at least one solvent selected from the group consisting of physiological saline solution, glucose injection solution, and replacement fluid, the lyophilized pharmaceutical composition being dissolved in a solvent.SELECTED DRAWING : NoneCOPYRIGHT : (C)2019, JPO&INPIT

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