PROBLEM TO BE SOLVED : To provide drug delivery devices having vacuum assisted securement and patient/operator feedback. SOLUTION : A drug delivery device 10 includes a housing 12 with a rigid base 12-2 which has a surface defining at least one pressure communication channel or aperture. The pressure communication channel or aperture distributes a negative fluid pressure across its base to draw tissue against the base. The drug delivery device may also include a porous, adhesive layer 62 over the pressure communication channel(s) or aperture(s), for adhesively attaching the drug delivery device to tissue. The pressure communication channel or aperture distributes the negative fluid pressure across the adhesive layer to allow the tissue drawn against the adhesive layer. The drug delivery device may also include a pressure sensor for determining whether or not the device is properly attached to the body tissue by the adhesive layer. SELECTED DRAWING : Figure 1 COPYRIGHT : (C)2019, JPO&INPIT