专利名称 | ALKYNYL-SUBSTITUTED HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF. | ||
申请号 | MX2019003143 | 申请日 | |
公开(公告)号 | MX2019003143A | 公开(公告)日 | |
申请(专利权)人 | BEIJING INNOCARE PHARMA TECH CO LTD | 发明人 | XIANGYANG CHEN; YINGXIANG GAO; NORMAN XIANGLONG KONG |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
The present invention relates to an alkynyl-substituted heterocyclic compound acting as an FGFR inhibitor, a preparation method therefor and the medical use thereof. In particular, the present invention relates to a compound as shown in general formula (I) and a pharmaceutically acceptable salt thereof; a pharmaceutical composition including the compound or a pharmaceutically acceptable salt thereof; a method for treating and/or preventing FGFR-associated diseases, particularly tumours, by using the compound or a pharmaceutically acceptable salt thereof; and a preparation method for the compound or a pharmaceutically acceptable salt thereof. The present invention also relates to the use of the compound or a pharmaceutically acceptable salt thereof, or the pharmaceutical composition including the compound or a pharmaceutically acceptable salt thereof in the preparation of a drug for treating and/or preventing FGFR-associated diseases, particularly tumours, wherein the definition of each substituent in general formula (I) is the same as that in the description. |
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