| 专利名称 | OLIGONUCLEOTIDES FOR MODULATING FNDC3B EXPRESSION | ||
| 申请号 | WOEP18084075 | 申请日 | |
| 公开（公告）号 | WO2019115416A2 | 公开（公告）日 | |
| 申请（专利权）人 | ROCHE INNOVATION CENTER COPENHAGEN A/S | 发明人 | HAGEDORN Peter; PEDERSEN Lykke |
| 专利来源 | 国家知识产权局 | 转化方式 | |
| 摘要 |
The present invention relates to antisense oligonucleotides that are capable of modulating expression of FNDC3B in a target cell. The oligonucleotides hybridize to FNDC3B pre-mRNA or mRNA. The present invention further relates to conjugates of the oligonucleotide and pharmaceutical compositions and methods for treatment of cancers, such as hepatocellular carcinoma or acute myeloid leukemia using the oligonucleotide. |
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