| 专利名称 | COMBINATORY TREATMENT | ||
| 申请号 | JP2019011857 | 申请日 | |
| 公开(公告)号 | JP2019094339A | 公开(公告)日 | |
| 申请(专利权)人 | AERIE PHARMACEUTICALS INC | 发明人 | CASEY KOPCZYNSKI; LIN CHENG WEN; JILL MARIE STURDIVANT; MITCHELL A DELONG |
| 专利来源 | 国家知识产权局 | 转化方式 | |
| 摘要 |
PROBLEM TO BE SOLVED : To provide a compound and a composition for treatment of glaucoma and/or for reducing ocular tension. SOLUTION : A compound selected from the group consisting of the followings a) to c) : a) 2, 4-dimethylbenzoic acid (rac)-4-(3-amino-1-(isoquinoline-6-ylamino)-1-oxopropane-2-yl)benzylic dimesylate salt, b) 2, 4-dimethylbenzoic acid (R)-4-(3-amino-1-(isoquinoline-6-ylamino)-1-oxopropane-2-yl)benzylic dimesylate salt, and, c) 2, 4-dimethylbenzoic acid (S)-4-(3-amino-1-(isoquinoline-6-ylamino)-1-oxopropane-2-yl)dimethylbenzoic acid. The composition may contain an isoquinoline compound and a prostaglandin or a prostaglandin analogue. SELECTED DRAWING : Figure 1 COPYRIGHT : (C)2019, JPO&INPIT |
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