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专利概况
专利名称 Instant release capsule based on hot melt extruded polyvinyl alcohol
申请号 AU2017353325 申请日
公开(公告)号 AU2017353325A1 公开(公告)日
申请(专利权)人 Merck Patent GmbH 发明人 Zheng Mengyao; Knuettel Anja Nadine
专利来源 国家知识产权局 转化方式
摘要

The present invention relates to an improved powdered extrudate based on polyvinyl alcohol (PVA), which can be used for pharmaceutical products, and that, due to its improved properties, can be better filled into capsules and the capsules show stable immediate drug release kinetic without problem of particle aggregation. Furthermore, this invention refers to pharmaceutical capsule composition comprising extruded polyvinyl alcohol as carrier matrix and can improve the solubility of API within immediate release kinetic. Moreover, the capsule show also benefit than tablet regarding to the material cost, because just PVA and API, no additional excipients are needed for capsule.

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