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专利概况
专利名称 GPR119 AGONIST
申请号 US13575978 申请日
公开(公告)号 US20190192510A1 公开(公告)日
申请(专利权)人 NIPPON CHEMIPHAR CO LTD 发明人 Tsuyoshi ENDO; Rie TAKAHASHI; Hiroto TANAKA; Toshihiro KUNIGAMI
专利来源 国家知识产权局 转化方式
摘要

A compound represented by the following formula (I) or the formula (II) disclosed in the specification is a GPR119 agonist, and is used as an agent for treating diabetes : wherein one of T1, T2, T3, and T4 is N, and each of the other three independently is CR4 or, in the alternative, each of the four independently is CR4; each of R2 and R3 is hydrogen or a C1-8 alkyl group; the double line consisting of a solid line and a broken line means a single or double bond; A is (CH2)m, a bond, or the like; B is (C(R5)H)n, a bond, or the like; one of U and V is N, and the other is CR7; W is C or CR8; each of X and Y is a C1-3 alkylene group, which optionally has a halogen atom, hydroxyl etc.; Z is C(O)OR9, C(O)R10, or the like.

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