专利名称 | Salts of palbociclib | ||
申请号 | HU1500506 | 申请日 | |
公开(公告)号 | HU230962B1 | 公开(公告)日 | |
申请(专利权)人 | EGIS GYOGYSZERGYAR ZRT | 发明人 | DR LUKACS GYULA; DR MARVANYOS EDE LASZLO; DR BERECZ GABOR; HEDER JANOS LEVENTE; DR MILEN MATYAS; PEREGI BALAZS; GUDOR ROBERT; DR VOLK BALAZS; TOTHNE DR LAURITZ MARIA |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
The subject of the invention relates to various new salts of palbociclib, furthermore to their hydrate and solvate forms, such as the palbociclib hydrogen bromide (1 : 1) salt, the palbociclib hydrogen bromide (1 : 2) dihydrate salt, the palbociclib hydrogen chloride (1 : 1) salt Form E, the palbociclib sulphate (2 : 1) dihydrate salt, the palbociclib camsylate (1 : 1) salt, the palbociclib napsylate (1 : 1) salt, the palbociclib napsylate (1 : 2) dihydrate salt, the palbociclib tosylate (1 : 1) salt, the palbociclib citrate (1 : 1) monohydrate salt, the palbociclib maleate (1 : 1) salt Form I, the palbociclib maleate (1 : 1) salt Form II and the palbociclib oxalate (1 : 1) salt. The subject of the invention also relates to the production of the above palbociclib salts, medicinal preparations containing these and the medical use of the above forms. |
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