The present invention refers to real estate pink leaves (Acrosorium polyneurum) useful as anti-including prevention and treatment of inflammatory diseases which has an effect is directed to pharmaceutical compositions. Real estate of the present invention the leaf extract pink IL-12 p40, IL-6, TNF-α inflammatory cytokines such as JNK of inhibiting the production of which, such as p38 MAP and inhibiting the phosphorylation of kinases, disintegration and the inhibiting the phosphorylation of IκBα NF-κB capable of inhibiting the activation of a which, in macrophages, NO of suppressing the autoimmune diseases to for preventing and septic shock and can be used for therapeutic use.