专利名称 | THERAPEUTICS TARGETING TRUNCATED ADENOMATOUS POLYPOSIS COLI (APC) PROTEINS | ||
申请号 | EP14843412 | 申请日 | |
公开(公告)号 | EP3044218B1 | 公开(公告)日 | |
申请(专利权)人 | Board Of Regents Of the University Of Texas System | 发明人 | DEBRABANDER Jef; SHAY Jerry W; WANG Wentian |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
The described invention provides small molecule anti-cancer compounds that selectively target and inhibit measurable biological activity of truncated APC proteins, an immortalized Human Colonic Epithelial Cell (HCEC) model, and pharmaceutical compositions comprising at least one of the small molecule anti-cancer compounds and a pharmaceutically acceptable carrier. |
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