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专利概况
专利名称 ALKYNYL(HETERO)AROMATIC COMPOUND FOR INHIBITING PROTEIN KINASE ACTIVITY
申请号 WOCN19093469 申请日
公开(公告)号 WO2020007234A1 公开(公告)日
申请(专利权)人 SHENZHEN TARGETRX INC 发明人 WANG Yihan; XING Qingfeng
专利来源 国家知识产权局 转化方式
摘要

Provided is an alkynyl(hetero)aromatic compound having an inhibitory effect to protein tyrosine kinase, a pharmaceutical composition comprising same, preparation and usage thereof. Specifically, disclosed is an alkynyl(hetero)aromatic compound as shown in formula (I), wherein rings A, R 1, R 2, R 3, R 4, R 5, L, and B are defined in the description, a pharmaceutically acceptable salt, a stereisomer, a solvate, a hydrate, a crystal form, a prodrug or an isotopic variant thereof. The compound can be used for treating and/or preventing protein tyrosine kinase-related diseases, such as anti-tumor.

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