| 专利名称 | Alkyl cellulose for use in tableting and solid preparation comprising same | ||
| 申请号 | US16047531 | 申请日 | |
| 公开(公告)号 | US10532029B2 | 公开(公告)日 | |
| 申请(专利权)人 | SHIN ETSU CHEMICAL CO LTD | 发明人 | Takuya Yokosawa; Naosuke Maruyama |
| 专利来源 | 国家知识产权局 | 转化方式 | |
| 摘要 |
Provided are an alkyl cellulose excellent in formability when added even in a small amount and not causing marked delay in disintegration; a solid preparation comprising it; and a method for producing the solid preparation. More specifically, provided are an alkyl cellulose for use in tableting, the alkyl cellulose having a specific surface area of from 0.5 to 10.0 m2/g as measured by BET method and a solid preparation comprising the alkyl cellulose. Also provided is a method for producing the alkyl cellulose, comprising the steps of : bringing pulp into contact with an alkali metal hydroxide solution to obtain alkali cellulose, reacting the alkali cellulose with an etherifying agent to obtain a first alkyl cellulose, pulverizing the first alkyl cellulose, and depolymerizing the pulverized first alkyl cellulose through hydrolysis with an acid catalyst or through oxidative decomposition with an oxidant to obtain a second alkyl cellulose. |
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