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专利概况
专利名称 Alkyl cellulose for use in tableting and solid preparation comprising same
申请号 US16047531 申请日
公开(公告)号 US10532029B2 公开(公告)日
申请(专利权)人 SHIN ETSU CHEMICAL CO LTD 发明人 Takuya Yokosawa; Naosuke Maruyama
专利来源 国家知识产权局 转化方式
摘要

Provided are an alkyl cellulose excellent in formability when added even in a small amount and not causing marked delay in disintegration; a solid preparation comprising it; and a method for producing the solid preparation. More specifically, provided are an alkyl cellulose for use in tableting, the alkyl cellulose having a specific surface area of from 0.5 to 10.0 m2/g as measured by BET method and a solid preparation comprising the alkyl cellulose. Also provided is a method for producing the alkyl cellulose, comprising the steps of : bringing pulp into contact with an alkali metal hydroxide solution to obtain alkali cellulose, reacting the alkali cellulose with an etherifying agent to obtain a first alkyl cellulose, pulverizing the first alkyl cellulose, and depolymerizing the pulverized first alkyl cellulose through hydrolysis with an acid catalyst or through oxidative decomposition with an oxidant to obtain a second alkyl cellulose.

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