A heteroaryl derivative represented by general formula (I), a preparation method therefor, and a pharmaceutical composition comprising the derivative and a use thereof as a therapeutic agent, in particular as an A2a receptor and/or an A2b receptor antagonist and a use thereof in preparation of a medicament for treatment of conditions or symptoms that are ameliorated by inhibiting the A2a receptor and/or the A2b receptor. Various substituent groups in the general formula (I) have the identical meanings as those in the specification.