| 专利名称 | IMPROVED VIRUS-LIKE NANOPARTICLES FOR ORAL DELIVERY | ||
| 申请号 | WOUS19035823 | 申请日 | |
| 公开（公告）号 | WO2019236870A9 | 公开（公告）日 | |
| 申请（专利权）人 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 发明人 | CHENG R Holland; CHEN Chun Chieh; BAIKOGHLI Mohammad Ali; STARK Marie |
| 专利来源 | 国家知识产权局 | 转化方式 | |
| 摘要 |
A Hepatitis E virus (HEV)-based virus like nanoparticle (HEVNP) made with a modified capsid protein containing at least a portion of open reading frame 2 (ORF2) protein conjugated with gold nanocluster is provided. Also provided are methods of targeted delivery of a nucleic acid using the HEVNP. |
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