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专利概况
专利名称
申请号 DK16746062 申请日
公开(公告)号 DK3255046T3 公开(公告)日
申请(专利权)人 JIANGSU HENGRUI MEDICINE CO 发明人 WU GUAILI; GAO XIAOHUI; JIA JUNLEI
专利来源 国家知识产权局 转化方式
摘要

The present invention relates to a hydroxyethyl sulfonate of cyclin-dependent protein kinase inhibitor, a crystalline form thereof and a preparation method therefor. Specifically, the present invention relates to 6-acetyl-8-cyclopentyl-5-methyl-2-((5-(piperidin-4-yl)pyridin-2-yl)amino)pyrido[2, 3-d] pyrimidin-7(8H)-one hydroxyethyl sulfonate (compound of formula (I)), a crystal type I thereof and a preparation method therefor. Crystal type I of the compound shown in formula (I) obtained by the present invention has good chemical stability and crystalline stability, and has low toxicity and residue with respect to the solvent used for crystallization. Therefore, the crystal type I can be used in clinical therapy better.

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