| 专利名称 | Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use | ||
| 申请号 | US15112818 | 申请日 | |
| 公开（公告）号 | US10537573B2 | 公开（公告）日 | |
| 申请（专利权）人 | Janssen Pharmaceutica NV | 发明人 | Brian D Klein; Hilde Lavreysen; Stefan Maria Christiaan Pype; Roy E Twyman; Nancy Eulalie Sylvain Van Osselaer; H Steven White; Marc Andr?Ceusters; Jos?Maria Cid Nez; Andr閟 Avelino Trabanco Su醨ez; Roger Francis Bone |
| 专利来源 | 国家知识产权局 | 转化方式 | |
| 摘要 |
The present invention relates to combinations comprising a positive allosteric modulator (“PAM”) of metabotropic glutamatergic receptor subtype 2 (“mGluR2”) or a pharmaceutically acceptable salt or a solvate thereof, or an orthosteric agonist of metabotropic glutamatergic receptor subtype 2 compound or a pharmaceutically acceptable salt or a solvate thereof, and a synaptic vesicle protein 2A (“SV2A”) ligand. |
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