专利名称 | THERAPEUTIC USE OF AFATINIB IN CANCER | ||
申请号 | EP18382527 | 申请日 | |
公开(公告)号 | EP3597193A1 | 公开(公告)日 | |
申请(专利权)人 | Universitat Aut騨oma de Barcelona; Consorcio Centro de Investigaci髇 Biom閐ica en Red M P; Fundacio Institut de Recerca de l' Hospital de la Santa Creu i sant Pau | 发明人 | Surrall閟 Calonge Jordi; Minguill髇 Pedre駉 Jordi; Montanuy Escribano Helena |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
The present invention provides the afatinib or a pharmaceutically salt thereof for use in the treatment and/or prevention of a cancer in a patient suffering from a disease caused by a defect in DNA damage repair mechanism.Surprisingly, when afatinib was administered to FA cells, it was confirmed that there was a therapeutic anti-cancer effect without any toxic side-effect on DNA. |
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