| 专利名称 | COMPOSITIONS FOR TREATING RENAL AND/OR HEPATIC DISORDERS | ||
| 申请号 | RU2017135939 | 申请日 | |
| 公开(公告)号 | RU2712624C2 | 公开(公告)日 | |
| 申请(专利权)人 | ВЕКТУС БАЙОСИСТЕМС ЛИМИТЕД; VECTUS BIOSYSTEMS LIMITED | 发明人 | ДАГГЭН Карен Аннетт; ДАГГЭН Карен АннеттDUGGAN Karen Annette |
| 专利来源 | 国家知识产权局 | 转化方式 | |
| 摘要 |
FIELD : medicine; pharmaceuticals.SUBSTANCE : invention relates to compounds of formula given below or pharmaceutically acceptable salts thereof. In given formula A iseach of R1-R9 independently represents C, N, O or S; Q is independently selected from C1-6alkyl, halogen, C0-6alkylcarboxylic acid, amino, hydroxy and C1-6alkoxy; n equals 0, 1, 2, 3 or 4 and X represents -OH or wherein, if X is -OH, A can not be unsubstituted phenyl. Invention also relates to a pharmaceutical composition, a method for preventive or therapeutic treatment of the above diseases and conditions, use of the disclosed compounds for preparing a medicinal preparation for preventive or therapeutic treatment of the above diseases and conditions, as well as to intermediate compounds used in synthesis thereof.EFFECT : inventions can be used for preventive or therapeutic treatment of kidney and/or liver fibrosis, for preventing, reducing or decelerating cells death of renal tubules, preventing, reducing or retarding accumulation of fat in liver or restoration of normal tissue structure in a subject.24 cl, 19 dwg, 1 tbl, 12 exили - or |
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