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专利概况
专利名称 Mycobacterium tuberculosis H37RV proliferation inhibitor based on (?ethane-1, 2-diol-O, O' )-bis{[N-(2, 3-dimethylphenyl)-2-(oxy-3-methoxybenzylidene)hydrazinecarbothioamido(1-)]aquacopper(II)} nitrate
申请号 MD20180084 申请日
公开(公告)号 MD4671B1 公开(公告)日
申请(专利权)人 UNIV DE STAT DIN MOLDOVA 发明人 GULEA AURELIAN; CRUDU VALERIU; ŢAPCOV VICTOR
专利来源 国家知识产权局 转化方式
摘要

The invention relates to chemistry and medicine, namely to a biologically active coordination compound of copper from the class of transition metal thiosemicarbazonates. This complex inhibits the mycobacterium tuberculosis H37RV proliferation processes and can be used in medicine for the prevention and treatment of tuberculosis.According to the invention, claimed is (?ethane-1, 2-diol-O, O' )-bis{[N-(2, 3-dimethylphenyl)-2-(oxy-3-methoxybenzylidene)hydrazinecarbothioamido(1-)]aquacopper(II)} nitrate compound of the formula : , which inhibits the mycobacterium tuberculosis H37RV proliferation processes.The compound expands the arsenal of Mycobacterium tuberculosis proliferation inhibitors with high biological activity.

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